Dr. Daniel Beard, PhD, Associate Professor of the Department of Physiology and the Biotechnology and Bioengineering Center, has been awarded a grant from the National Institutes of Health, NHLBI, entitled, “Mechanisms of Metabolic Dysfunction in Heart Disease”, in the amount of $1,415,625, beginning on 01/01/2009.  This project is focused on determining how molecular-level changes in mitochondrial enzymes and transporters that occur in heart disease affect overall cardiac function and determining how therapies may be targeted at the molecular level to improve function at the whole-organ level.