KAPattern

Generating Rate Equations for Complex Enzyme Systems by a Simple Computer-Assisted Systematic Method

Feng Qi, Ranjan K. Dash, Yu Han, Daniel A. Beard

Biotechnology Bioengineering Center,
Department of Physiology, Medical College of Wisconsin

 

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KA Pattern generator is a Matlab based suite of tools for deriving enzyme kinetic flux expressions using topological theory of linear graphs for systematic generation of valid King and Altman patterns. This program can derive equations for both strict steady-state system and those with the assumption of rapid equilibrium, for either branched or unbranched mechanism which can contain both reversible and irreversible conversion step, and also can automatically generate an output files (Expression.m, Expression_MathML.html, ResultPage.html) which users can be easily plug into their own biomodel program as a module.